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MEG Special Interest Group at AES Annual Meeting

ACMEGS President Michael Funke, MD and Past President Richard C. Burgess, MD, PhD will lead a Special Interest Group at the upcoming AES Annual Meeting titled "Realistic Maps of Epileptic Source Extent from MEG: Fact or Fiction."

The SIG will be held on Tuesday, December 4, 7:00 - 8:30am, in Convention Center, Room 293, Second Floor.

Magnetoencephalography (MEG) non-invasively measures neural activity for presurgical evaluation of patients with intractable epilepsy. Interictal spikes are the hallmark of cortical epileptogenicity, and their spatial distribution in the cortex defines the irritative zone. Delineating that zone with desirable precision remains a challenge for epilepsy centers around the globe. Current clinical MEG practice still relies on dipole modeling of epileptic spikes alone. Do proposed methods like coherent Maximum Entropy of the Mean (cMEM) and Volumetric Imaging of Epileptic Spikes (VIES), allow a reasonable estimation of the volume of the spiking cortex? The program aims to highlight the most recent advances and remaining controversies in this fast-evolving field of computational neuro-electrophysiology by presentations and vivid discussion of international experts

The program for the SIG is as follows:

Inferring (Not Estimating) Source Extent Using the Okada Constant
John C. Mosher, PhD

Assessing the extent of the generators of epileptic discharges using MEG/EEG source imaging: validation and clinical relevance
Christophe Grova, PhD

What do different frequencies and other modalities tell us about MEG’s ability to identify the extent of the epileptic zone?
Akio Ikeda, MD, PhD, FACNS; and Masao Matsuhashi, MD, PhD